Publications

Mining cancer genomes for copy number alterations identifies glycosylation enzymes as oncogenic drivers.

Sahu P, Russo F, Russo D, Agliarulo I, Ambrosio P, Rizzo R, Lo Monte M, Normanno N, Soddu S, Carlomagno F, Luini A, Parashuraman S.

Proc Natl Acad Sci U S A (2026) 123(14):e2521848123.

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GRASP55 regulates intra-Golgi localization of glycosylation enzymes to control glycosphingolipid biosynthesis.

Pothukuchi P, Agliarulo I, Pirozzi M, Rizzo R, Russo D, Turacchio G, Nüchel J, Yang JS, Gehin C, Capolupo L, Hernandez-Corbacho MJ, Biswas A, Vanacore G, Dathan N, Nitta T, Henklein P, Thattai M, Inokuchi JI, Hsu VW, Plomann M, Obeid LM, Hannun YA, Luini A, D'Angelo G, Parashuraman S.

EMBO J. (2021) 40(20):e107766.

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Golgi maturation-dependent glycoenzyme recycling controls glycosphingolipid biosynthesis and cell growth via GOLPH3.

Rizzo R, Russo D, Kurokawa K, Sahu P, Lombardi B, Supino D, Zhukovsky MA, Vocat A, Pothukuchi P, Kunnathully V, Capolupo L, Boncompain G, Vitagliano C, Zito Marino F, Aquino G, Montariello D, Henklein P, Mandrich L, Botti G, Clausen H, Mandel U, Yamaji T, Hanada K, Budillon A, Perez F, Parashuraman S, Hannun YA, Nakano A, Corda D, D'Angelo G, Luini A.

EMBO J. (2021) 40(8):e107238.

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Role of the Mosaic Cisternal Maturation Machinery in Glycan Synthesis and Oncogenesis.

Sahu P, Balakrishnan A, Di Martino R, Luini A, Russo D.

Front Cell Dev Biol. (2022) 10:842448.

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GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer.

Scott KL, Kabbarah O, Liang MC, Ivanova E, Anagnostou V, Wu J, Dhakal S, Wu M, Chen S, Feinberg T, Huang J, Saci A, Widlund HR, Fisher DE, Xiao Y, Rimm DL, Protopopov A, Wong KK, Chin L.

Nature (2009) 459(7250):1085-90.

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